Douglas J DeMarini Selected Research

parsaclisib

9/2023	Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory follicular lymphoma (CITADEL-203): a phase 2 study.
8/2023	Parsaclisib, a PI3Kδ inhibitor, in relapsed and refractory mantle cell lymphoma (CITADEL-205): a phase 2 study.
1/2021	Phase 2 study of parsaclisib (INCB050465), a highly selective, next-generation PI3Kδ inhibitor, in relapsed or refractory diffuse large B-cell lymphoma (CITADEL-202).
1/2019	Parsaclisib, a potent and highly selective PI3Kδ inhibitor, in patients with relapsed or refractory B-cell malignancies.

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Douglas J DeMarini Research Topics

Disease

7	Melanoma (Melanoma, Malignant) 04/2016 - 08/2012
4	Neoplasms (Cancer) 09/2023 - 09/2013
2	Fever (Fevers) 08/2015 - 11/2014
1	Follicular Lymphoma (Lymphoma, Small Cleaved Cell, Follicular) 09/2023
1	Mantle-Cell Lymphoma (Lymphoma, Mantle Cell) 08/2023
1	Diffuse Large B-Cell Lymphoma (Lymphoma, Large Cell, Diffuse) 01/2021
1	Respiratory Insufficiency (Respiratory Failure) 01/2019
1	Sepsis (Septicemia) 01/2019
1	Body Weight (Weight, Body) 04/2016
1	Constipation 05/2015
1	Vomiting 05/2015
1	Nausea 05/2015
1	Pain (Aches) 05/2015
1	Squamous Cell Carcinoma (Epidermoid Carcinoma) 11/2014

Drug/Important Bio-Agent (IBA)

7	trametinibIBA 04/2016 - 08/2012
5	Mitogen-Activated Protein Kinase Kinases (MEKs)IBA 04/2016 - 08/2012
4	parsaclisibIBA 09/2023 - 01/2019
4	dabrafenibIBA 08/2015 - 09/2013
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 01/2019
1	itacitinibIBA 01/2019
1	Rituximab (Mabthera)FDA Link 01/2019
1	Alanine Transaminase (SGPT)IBA 01/2019
1	Aspartic Acid (Aspartate)FDA Link 01/2019
1	Etoposide (VP 16)FDA LinkGeneric 01/2019
1	Ifosfamide FDA LinkGeneric 01/2019
1	Carboplatin (JM8)FDA LinkGeneric 01/2019
1	Janus Kinase 1IBA 01/2019
1	omipalisibIBA 09/2013

Therapy/Procedure

2	Drug Therapy (Chemotherapy) 01/2019 - 02/2013
1	Immunotherapy 02/2013